Table of Contents

Communications

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Implications for OLE RNA as a natural integral membrane RNA
- Seth E. Lyon and
- Ronald R. Breaker
RNA August 2025 31: 1031-1040; Published in Advance May 20, 2025, doi:10.1261/rna.080489.125
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Copy number determination of sperm-borne small RNAs implied in the intergenerational inheritance of metabolic syndromes
- Lisa König,
- Victoria Guggenberger,
- Kristeli Eleftheriou,
- Zsuzsanna Pinter,
- Alessandro Marotto,
- Christoph R. Kreutz,
- Mark Wossidlo,
- Virginie Marchand,
- Yuri Motorin,
- and Matthias R. Schaefer
RNA August 2025 31: 1041-1052; Published in Advance May 28, 2025, doi:10.1261/rna.080480.125
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Review

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RNA G-quadruplex structure targeting and imaging: recent advances and future directions
- Tian-Ying Wu,
- Hill Lam Lau,
- Rachelle J. Santoso,
- and Chun Kit Kwok
RNA August 2025 31: 1053-1080; Published in Advance June 5, 2025, doi:10.1261/rna.080587.125
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RNA Therapeutics

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Absolute quantification of mammalian microRNAs for therapeutic RNA cleavage and detargeting
- Carolyn Kraus,
- Jiayi Wang,
- Haiying Zheng,
- Jennifer Broderick,
- Nandagopal Ajaykumar,
- Mina Zamani,
- Mengqi Yang,
- Katharine Cecchini,
- Shun-qing Liang,
- Olena Kolumba,
- Kathryn Chase,
- Jooyoung Lee,
- Wen Xue,
- Erik J. Sontheimer,
- and Ildar Gainetdinov
RNA August 2025 31: 1081-1090; Published in Advance May 28, 2025, doi:10.1261/rna.080566.125
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OpenASO: RNA Rescue—designing splice-modulating antisense oligonucleotides through community science
- Victor Tse,
- Martin Guiterrez,
- Jill Townley,
- Jonathan Romano,
- Jennifer Pearl,
- Guillermo Chacaltana,
- Eterna Players,
- Rhiju Das,
- Jeremy R. Sanford,
- and Michael D. Stone
RNA August 2025 31: 1091-1102; Published in Advance May 27, 2025, doi:10.1261/rna.080288.124

Bioinformatics and Databases

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Evaluation of novel computational methods to identify RNA-binding protein footprints from structural data
- Orel Mizrahi,
- Meredith Corley,
- Ori Feldman,
- Thorben Fröhlking,
- Lei Sun,
- Alison Ziesel,
- Maciej Antczak,
- Mattia Bernetti,
- Shaimae I. Elhajjajy,
- Wenze Huang,
- Grady G. Nguyen,
- Samuel S. Park,
- Raul I. Perez Martell,
- Luke Trinity,
- Kui Xu,
- Tomasz Zok,
- Giovanni Bussi,
- Hosna Jabbari,
- Yaron Orenstein,
- Sharon Aviran,
- Michelle M. Meyer,
- and Gene W. Yeo
RNA August 2025 31: 1103-1124; Published in Advance May 21, 2025, doi:10.1261/rna.080215.124

RNA and Gene Expression

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Tissue-specific SEC31A alternative splicing is regulated by RBM47 and controls lipid transport
- Felix Ostwaldt,
- Sarah Plößner,
- Benjamin Dimos-Röhl,
- Marco Preussner,
- and Florian Heyd
RNA August 2025 31: 1125-1138; Published in Advance May 28, 2025, doi:10.1261/rna.080572.125
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Structural and functional characterization of the SLA′ structure at the 3′ terminus of the Zika virus negative-strand intermediate
- Quinn H. Abram,
- Lindsay A. Matthews,
- Alba Guarné,
- and Selena M. Sagan
RNA August 2025 31: 1139-1153; Published in Advance May 8, 2025, doi:10.1261/rna.080342.124
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Alu RNA pseudoknot alterations influence SRP9/SRP14 association
- Daniel Gussakovsky,
- Mira J.F. Brown,
- Higor Sette Pereira,
- Markus Meier,
- G. Pauline Padilla-Meier,
- Nicole A. Black,
- Evan P. Booy,
- Jörg Stetefeld,
- Trushar R. Patel,
- and Sean A. McKenna
RNA August 2025 31: 1154-1175; Published in Advance May 9, 2025, doi:10.1261/rna.080359.124
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EDC4 C-terminal domain scaffolds P-body assembly and links P-body dynamics to p53-mediated tumor suppression
- Yu-Hsuan Cheng,
- Ting-Wen Chen,
- Wei-Chung Chiang,
- Jean-Cheng Kuo,
- Yi-Sheng Ho,
- Michelle Noble,
- and Chung-Te Chang
RNA August 2025 31: 1176-1194; Published in Advance May 13, 2025, doi:10.1261/rna.080561.125
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Human CCR4 deadenylase homolog Angel1 is a non-stop mRNA decay factor
- Tim Nicholson-Shaw,
- Megan E. Dowdle,
- Yasmeen Ajaj,
- Mark Perelis,
- Amit Fulzele,
- Gene W. Yeo,
- Eric J. Bennett,
- and Jens Lykke-Andersen
RNA August 2025 31: 1195-1205; Published in Advance May 29, 2025, doi:10.1261/rna.080399.125
OPEN ACCESS ARTICLE

Communications

Implications for OLE RNA as a natural integral membrane RNA

Copy number determination of sperm-borne small RNAs implied in the intergenerational inheritance of metabolic syndromes

Review

RNA G-quadruplex structure targeting and imaging: recent advances and future directions

RNA Therapeutics

Absolute quantification of mammalian microRNAs for therapeutic RNA cleavage and detargeting

OpenASO: RNA Rescue—designing splice-modulating antisense oligonucleotides through community science

Bioinformatics and Databases

Evaluation of novel computational methods to identify RNA-binding protein footprints from structural data

RNA and Gene Expression

Tissue-specific SEC31A alternative splicing is regulated by RBM47 and controls lipid transport

Structural and functional characterization of the SLA′ structure at the 3′ terminus of the Zika virus negative-strand intermediate

Alu RNA pseudoknot alterations influence SRP9/SRP14 association

EDC4 C-terminal domain scaffolds P-body assembly and links P-body dynamics to p53-mediated tumor suppression

Human CCR4 deadenylase homolog Angel1 is a non-stop mRNA decay factor

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