Contribution of an alternative 16S rRNA helix to biogenesis of the 30S subunit of the ribosome

TABLE 1.

Growth of control and mutant Δ7 prrn strains

Strain 16S Allele Doubling timea Pb
BRW176 WT 31.3 ± 0.9 N/Ac
BRW205 U1532A/C1533G 37.7 ± 0.5 0.0000041
BRW206 U1532C/C1533U 35.1 ± 0.5 0.0033
  • aUnits of minutes. Data represent mean ± SEM of at least three biological replicates.

  • bA two-tailed t-test was used to evaluate differences from the WT, and the resulting uncorrected P-values are reported.

  • cNot applicable.

This Article

  1. RNA 30: 770-778