Contribution of an alternative 16S rRNA helix to biogenesis of the 30S subunit of the ribosome

Structural basis of the active-to-inactive transition. Comparison of the 30S subunit in the active (A) and inactive (B) states, viewed from the 50S perspective. On the left are structures of the 30S where h28, h44, and h45 are colored red. Major regions of the subunit have been labeled. Panels show the relevant regions magnified with h28 (teal), h44 (orange), hALT (yellow), and the 3′ end of the 16S rRNA (purple). On the right are corresponding secondary structure diagrams with the same coloring scheme. (ASD) Anti-Shine–Dalgarno. This figure was made using PyMOL (PDB 6W6K, 6W77) and StructureEditor 1.0 (Mathews Lab).