Identification of 3D motifs in Rfam with JAR3D

TABLE 3.

Motif groups that have the largest number of Rfam loops that match them with a cutoff score above set thresholds, among Rfam families that are not mapped to a 3D structure

Motif group Description # core Cutoff # matches
HL_53890.2 Three conserved stacks, one or two bulged bases 5 80 60
HL_75660.5 One conserved stack, multiple bulged bases 3 80 47
HL_32346.4 One conserved stack, multiple bulged bases 3 80 41
HL_52953.3 Four conserved stacks, occurs in riboswitches, ribozymes 6 80 39
HL_04783.2 GNRA variation 5 80 38
HL_50006.2 Two conserved stacks, multiple bulged bases 4 80 28
HL_37824.7 GNRA hairpin 6 80 28
IL_87907.2 Isolated noncanonical cWW pair 6 80 1216
IL_07785.1 Isolated noncanonical cWW pair 6 80 804
IL_44465.1 Isolated noncanonical GG cWW contact 6 80 530
IL_42997.3 Isolated noncanonical cWW/cWS pair 6 80 525
IL_67095.2 Isolated tWW turn 6 80 504
IL_08770.1 Isolated noncanonical pair 6 80 473
IL_14688.1 Isolated noncanonical cWW pair 6 80 464
IL_28037.2 Isolated noncanonical cWW pair 6 80 340
IL_42771.1 Multiple bulged bases 4 80 327
IL_10167.6 Isolated cWH base pair, usually GG 6 80 298
IL_31737.3 One conserved stack, one bulged 5 80 286
IL_57744.1 Isolated noncanonical cWW pair 6 80 212
IL_82107.4 Multiple bulged bases 4 80 124
IL_77658.1 Tandem noncanonical cWW pairs 8 80 87
J3_07845.1 Nearly minimal, one instance in the motif group 7 60 4
J3_41486.2 Coaxial stacking, recurrent 8 60 3
J3_11375.2 Coaxial stacking, recurrent 10 60 2
J3_70599.1 Coaxial stacking, recurrent 11 60 2
J4_00691.2 Minimal J4, two coaxial stacks, recurrent 8 60 3
J4_76096.5 Minimal J4, two coaxial stacks, recurrent 8 60 2
J4_24280.2 Minimal J4, two coaxial stacks, from LSU 8 60 1
  • Column 1 lists the motif group identifier, Column 2 gives a brief description of the instances in the motif group, Column 3 tells the number of core positions in the motif group (which does not count bulged bases), Column 4 tells the cutoff score threshold, and Column 5 tells the number of Rfam loops that match at or above the cutoff score threshold.

This Article

  1. RNA 32: 555-567