Structural analysis of the lncRNA SChLAP1 reveals protein binding interfaces and a conformationally heterogenous retroviral insertion

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FIGURE 4.
FIGURE 4.

ΔSHAPE analysis of SChLAP1. Significant in-cell protected or enhanced regions identified in both replicates of ΔSHAPE (see Materials and Methods) are mapped over a representative MFE structure of ex cellulo SChLAP1. SChLAP1 structure visualized in VARNA (Darty et al. 2009).

This Article

  1. Published in Advance June 11, 2025, doi: 10.1261/rna.080488.125 RNA 31: 1260-1286

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