Phylogenetic analysis of SChLAP1. (A) BLAST search of isoform 4 of SChLAP1 (containing all possible human exons) against the RefSeq database. (Top) Isoform 4 of SChLAP1 with each exon shown for reference. The 3′-positions of each exon in the human SChLAP1 are labeled. (Bottom) Sequence alignments of all identified SChLAP1 homologs against human SChLAP1 isoform 4. The 5′- and 3′-positions of alignment against human SChLAP1 are noted. All BLAST alignment scores were >200. Asterisk denotes Pan troglodytes aligning at nucleotides 1006 rather than 1007. (B) PhyloP analysis of SChLAP1 isoform 4 using phyloP 30-way (top) or 447-way (bottom). Figure generated in Integrative Genomics Viewer (Robinson et al. 2011). (C) RepeatMasker analysis of SChLAP1 Iso. 1 (see also Supplemental Fig. S1).
