Rho-dependent transcription termination: mechanisms and roles in bacterial fitness and adaptation to environmental changes

(Downloading may take up to 30 seconds. If the slide opens in your browser, select File -> Save As to save it.)

Click on image to view larger version.

FIGURE 7.
FIGURE 7.

Cryo-EM reconstructions of the λN (PDB 6GOV) and rnn (PDB 6TQO) antitermination complexes show how the antitermination factors bind RNAP and the nascent transcript to shield them efficiently from Rho action (compare with Fig. 2B,D). The complexes also sequester NusG-CTD (by NusE) and prevent RNAP pausing or backtracking (Krupp et al. 2019; Huang et al. 2020).

This Article

  1. Published in Advance June 3, 2025, doi: 10.1261/rna.080486.125 RNA 31: 1207-1234

Current Issue

  1. July 2026, 32 (7)
  1. Current Issue
  1. Alert me to new issues of RNA