Structural and functional characterization of the SLA′ structure at the 3′ terminus of the Zika virus negative-strand intermediate

TABLE 1.

Predicted Gibbs free energy of SLA and SLA′ in ZIKV and DENV

Virus Positive strand Negative strand
Structure ΔG (kcal/mol) Structure ΔG (kcal/mol)
ZIKV SLA −21.6 SLA′ −16.1
DENV1 SLA −17.4 SLA′ −16.4
DENV2 SLA −21.7 SLA′ −20.0
DENV3 SLA −19.2 SLA′ −11.3
DENV4 SLA −18.6 SLA′ −20.2

This Article

  1. Published in Advance May 8, 2025, doi: 10.1261/rna.080342.124 RNA 31: 1139-1153

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