Crystallographic and cryoEM analyses reveal SARS-CoV-2 SL5 is a mobile T-shaped four-way junction with deep pockets

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FIGURE 4.
FIGURE 4.

Single-particle cryogenic sample electron microscopy (cryoEM) analysis indicates a dynamic four-way junction and a SL5a swivel. (A) Coulomb potential map for stem–loop 5 (SL5) contoured at 10 σ in PyMOL (blue mesh) overlaid on the crystal structure (Cs+ derivative), colored as in Figure 1. (B) Orthogonal view.

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  1. RNA 31: 949-960

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