An MST-based assay reveals new binding preferences of IFIT1 for canonically and noncanonically capped RNAs

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FIGURE 1.
FIGURE 1.

Structures of canonical and noncanonical RNA caps studied in this work. Structures of the (A) canonical and (B) noncanonical RNA 5′ cap analogs used for RNA preparation by IVT. (C) The workflow for RNA preparation and purification leading to highly homogenous 5′ capped RNA.

This Article

  1. Published in Advance December 6, 2024, doi: 10.1261/rna.080089.124 RNA 31: 181-192

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