Investigating the role of RNA-binding protein Ssd1 in aneuploidy tolerance through network analysis

RBPs share enriched features among bound targets. Distributions of PARS scores (Kertesz et al. 2010) representing RNA secondary structure (top) or encoded-protein IUPred scores (Dosztányi 2018) representing predicted disorder (bottom) for RNAs bound by each RBP; see Materials and Methods for details. The number of mRNAs plotted is listed above each RBP name. (***) FDR < 0.00001, (**) 0.00001 ≤ FDR < 0.001, (*) 0.001 ≤ FDR < 0.05, two-sided Mann–Whitney U test with Benjamini and Hochberg FDR correction (Benjamini and Hochberg 1995).