Mapping RNA–protein interactions with subcellular resolution using colocalization CLIP

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FIGURE 5.
FIGURE 5.

Gene level features of subcellular HuR targeting from coCLIP. (A) Stress versus mock comparisons of G3BP1 coCLIP data with respective mock conditions compared to matched gene level RNA-seq data. (B) Transcript length boxplots for input or coCLIP-derived HuR targets. Outliers are omitted for clarity. (C) Gene ontology analysis of HuR binding sites from input CLIP or compartment-specific coCLIP under mock or arsenite stress conditions. Individual gene ontology terms are shown in the right. Dot size represents statistical significance after FDR correction. Manually curated grouped GO terms are shown on the left. See also Supplemental Figure S6.

This Article

  1. RNA 30: 920-937