A new reagent for in vivo structure probing of RNA G and U residues that improves RNA structure prediction alone and combined with DMS

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FIGURE 7.
FIGURE 7.

Prediction accuracy for folding of rRNA domains from Escherichia coli in RNAstructure quantified by the MCC. Folding was done with four sets of reactivity restraints: (1) sequence alone (gray circles), (2) ETC reactivities at Gs and Us as restraints (aqua triangles), (3) DMS reactivities at As and Cs as restraints (red squares), and (4) ETC and DMS reactivities combined (yellow diamonds).

This Article

  1. Published in Advance April 26, 2024, doi: 10.1261/rna.079974.124 RNA 30: 901-919

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