Examining the capacity of human U1 snRNA variants to facilitate pre-mRNA splicing

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FIGURE 2.
FIGURE 2.

Low expression of U1 snRNAs from endogenous loci in human cell lines. Expression levels of snRNAs were measured by RT-qPCR. The expression values for vU1s were calculated relative to the canonical U1 snRNA and normalized to the U2 snRNA (n = 3) in HeLa, HEK293T, K562, MV-4-11, and TF-1a cells. vU1A6* was not tested in HEK293T cells. Sequences of primer sets used for RT-qPCR are provided in Supplemental Table S2.

This Article

  1. Published in Advance December 27, 2023, doi: 10.1261/rna.079892.123 RNA 30: 271-280

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