tRNAVal allows four-way decoding with unmodified uridine at the wobble position in Lactobacillus casei

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FIGURE 5.
FIGURE 5.

Ribosome A-site binding activity of native L. casei tRNAVal. GUU, GUC, GUA, GUG, and CCA (proline codon) are codons at the A site of the ribosomes. Aminoacylated native L. casei tRNAVal loaded with 14C-Val using ValRS bound not only to mRNA with GUA or GUG at the A site, but also to mRNA with GUU or GUC. Error bars are SEM for three independent experiments.

This Article

  1. Published in Advance September 10, 2024, doi: 10.1261/rna.080155.124 RNA 30: 1608-1619

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