Improved functions for nonlinear sequence comparison using SEEKR

TABLE 1.

Top 10 most XIST-similar lncRNAs, as assessed by overall k-mer content

Transcript ID Gene name Transcript length r-value Adj. P-value
ENST00000626826.1 HELLPAR 205,012 0.476 0
ENST00000570269.2 ENSG00000259976 15,214 0.359 5.54×10−08
ENST00000663028.1 ENSG00000286473 6197 0.344 2.27×10−07
ENST00000623833.1 ENSG00000279717 2679 0.330 7.94×10−07
ENST00000648200.2 LINC00632 21,234 0.327 8.96×10−07
ENST00000562952.1 ENSG00000261654 5985 0.325 9.22×10−07
ENST00000617901.1 ENSG00000277151 5305 0.324 9.22×10−07
ENST00000430027.3 DLX6-AS1 15,364 0.321 1.08×10−06
ENST00000566193.1 ENSG00000260197 2666 0.320 1.10×10−06
ENST00000667505.1 PCDH10-DT 8044 0.314 1.74×10−06
  • We evaluated the set of nonidentical “Ensembl_canonical” GENCODE v43 lncRNA transcripts that were ≥500 nt in length. Transcript length is shown in nucleotides. SEEKR-derived P-values were adjusted using the Benjamini–Hochberg method.

This Article

  1. RNA 30: 1408-1421