Study of the RNA splicing kinetics via in vivo 5-EU labeling

Regression model reflecting an influence of all transcript and SS features on the rate of splicing. (A) CDF-quantile regression model fitting for SS SpRs. (Left) Coefficients and significance for different numerical (top) and categorical (bottom) variables. Dots correspond to medians with lower and upper error bars showing 25% and 75% quantiles. Color corresponds to the coefficient being < or > 0. Size corresponds to −log₁₀(FDR), and transparency corresponds to FDR being < or > 0.05. (B) The distribution of SS SpRs (top) and scatter plots demonstrating the correlations between fitted and real SpR for donor (middle) and acceptor (bottom) SS. Red line corresponds to y = x.