Translation regulation by a guanidine-II riboswitch is highly tunable in sensitivity, dynamic range, and apparent cooperativity

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FIGURE 5.
FIGURE 5.

(A) Bioinformatic consensus of the gdm-II riboswitch class. (B) Biochemical consensus of the P. aeruginosa gdm-II riboswitch. (C) Conserved P1 binding pocket nucleotides. (D) Representation of the stacking interaction between A21 from P1 and A53 from P2. (E) Response profiles of two linker nucleotide variants with marked functional deficiencies.

This Article

  1. Published in Advance May 2, 2023, doi: 10.1261/rna.079560.122 RNA 29: 1126-1139

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