Structural and dynamic effects of pseudouridine modifications on noncanonical interactions in RNA

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FIGURE 6.
FIGURE 6.

Average heavy atom per residue RMSF for the RNA backbone (left) and the RNA bases (right) in MD simulations of selected ψ replacement variants of the WT NSR. The inset on the right highlights the region corresponding to the U-turn loop. RNA backbone refers to the atoms P, OP1, OP2, O5′, C5′, C4′, C3′, and O3′ of each nucleotide. Average structures of each MD simulation ensemble were used as references.

This Article

  1. Published in Advance March 3, 2023, doi: 10.1261/rna.079506.122 RNA 29: 790-807

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