Structural and dynamic effects of pseudouridine modifications on noncanonical interactions in RNA

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FIGURE 4.
FIGURE 4.

Dissociation free-energy ΔGdiss at T = 25°C for the signature HB1 interaction (left) and the hydrogen bonds involving the U/ψ13 H3 and U/ψ18 H3 protons (middle and right, respectively) in the WT NSR (gray) and the variants U14ψ (red), U13ψ (blue), and U18ψ (green). The dashed lines correspond to ΔGdiss for the interactions in the WT NSR.

This Article

  1. Published in Advance March 3, 2023, doi: 10.1261/rna.079506.122 RNA 29: 790-807

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