Computational design and experimental verification of pseudoknotted ribozymes

(Downloading may take up to 30 seconds. If the slide opens in your browser, select File -> Save As to save it.)

Click on image to view larger version.

FIGURE 4.
FIGURE 4.

In-line probing of glmS ribozymes. Designed glmS ribozyme structures were compared to the WT glmS ribozyme by in-line probing. (A) Design template with consensus sequence. (B) Secondary structure of glmS WT. (C) glmS2 shows more similarity to the WT in the degradation profile (red boxes).

This Article

  1. Published in Advance March 3, 2023, doi: 10.1261/rna.079148.122 RNA 29: 764-776

Current Issue

  1. July 2026, 32 (7)
  1. Current Issue
  1. Alert me to new issues of RNA