Spliceosome assembly and regulation: insights from analysis of highly reduced spliceosomes

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FIGURE 9.
FIGURE 9.

The SF3B complex from the Sc Bact complex (PDB 5GM6), showing both (A) Cm homology model and (B) electrostatic surface representations. Ysf3, shown in black, is absent in the Cm SF3B complex. In A, all protein sequences were annotated by conservation with their Cm homologs. Identical and similar amino acids are colored purple while dissimilar amino acids are colored wheat. mRNA is colored cyan. In B, the protein surface is colored from blue (electropositive) to red (electronegative) with mRNA as in A.

This Article

  1. RNA 29: 531-550