Translational control by Trypanosoma brucei DRBD18 contributes to the maintenance of the procyclic state

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FIGURE 2.
FIGURE 2.

Depletion of DRBD18 in procyclic cells leads to translational defects. (A) Polysomal profiles of lysates from PF DRBD18 RNAi cells either uninduced (red) or doxycycline-induced (blue). (Inset) Western blot of induced and uninduced whole cell samples showing efficient knockdown of DRBD18; p22 is used as a loading control. (B) Quantification of the monosome to polysome ratio from four independent experiments as in (A).

This Article

  1. Published in Advance September 20, 2023, doi: 10.1261/rna.079625.123 RNA 29: 1881-1895

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