SAFB associates with nascent RNAs and can promote gene expression in mouse embryonic stem cells

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FIGURE 7.
FIGURE 7.

SAFB puncta are largely distinct from nuclear speckles. (A) Dual antibody-staining in WT and DKO ESCs examining the location of nuclear speckles (via SC35) (Ilik et al. 2020) relative to SAFB. White arrows, individual cells shown under increased digital zoom in (B) (genotypes displayed above each zoomed image). (C) Dual antibody-staining in WT ESCs examining the location of SRSF1, SRSF3, and SRSF6 relative to SAFB.

This Article

  1. Published in Advance July 19, 2023, doi: 10.1261/rna.079569.122 RNA 29: 1535-1556

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