Structure of the dengue virus RNA promoter

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FIGURE 7.
FIGURE 7.

(A) Superposition of the 10 NMR structures of DenvSLATL (left), the structure with the lowest calculated energy (middle), and the secondary structure (right) are also shown. (B) A close-up view of the U-rich bulge of DenvSLATL. Two conformations of U-UU bulge were observed in the calculated NMR structures, as shown in the image. (C) The lowest energy structure of DenvSLATL in cartoon representation superposed on the SAXS envelope; the SAXS results were not used for refinement and therefore provide independent validation of the NMR structure.

This Article

  1. RNA 28: 1210-1223