Splicing efficiency of minor introns in a mouse model of SMA predominantly depends on their branchpoint sequence and can involve the contribution of major spliceosome components

Schematic representation of the reporters used for in vitro splicing experiments. The name of the corresponding gene, the U12 and U2 scores of the minor introns and the size of the exons and introns are indicated. Exonic sequences (gray boxes), minor splicing signals (splice donor, branchpoint sequence, and splice acceptor), as well as downstream sequences containing the major splice donor site are in capital letters.