Frame-shifted proteins of a given gene are unlikely to retain the same function
- Center for Biomolecular Sciences and Department of Pharmaceutical Sciences, University of Illinois at Chicago, 900 S. Ashland Avenue, Chicago, Illinois 60607, USA
- Corresponding author: shura{at}uic.edu
Abstract
In a recently published paper, Huang and coworkers claim that proteins translated in different reading frames from the same mRNA can have similar functions. This conclusion is possibly incorrect due to the possibility that the wild-type protein could still be expressed.
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Article is online at http://www.rnajournal.org/cgi/doi/10.1261/rna.076398.120.
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Freely available online through the RNA Open Access option.
- Received May 13, 2020.
- Accepted May 30, 2020.
This article, published in RNA, is available undera Creative Commons License (Attribution-NonCommercial 4.0 International), as described at http://creativecommons.org/licenses/by-nc/4.0/.
