Frameshifted proteins of a given gene are unlikely to retain the same function
Abstract
The paper of Huang et al. (Nucleic Acids Res., 2020, vol. 48, pp. 4396-4404) claims that proteins translated in different reading frames from the same mRNA can have similar functions. This conclusion is possibly incorrect due to the possibility that the wild type protein could still be expressed.
Keywords
- Received May 13, 2020.
- Accepted May 30, 2020.
- Published by Cold Spring Harbor Laboratory Press for the RNA Society
This article, published in RNA, is available under a Creative Commons License (Attribution-NonCommercial 4.0 International), as described at http://creativecommons.org/licenses/by-nc/4.0/.
