Cover image

Homology model of the mammalian 80S ribosome based on cryoelectron microscopy maps (Protein Data Bank code: 4cxh; Budkevich TV, Giesebrecht J, Behrmann E, Loerke J, Ramrath DJ, Mielke T, Ismer J, Hildebrand PW, Tung CS, Nierhaus KH, et al. 2014. Regulation of the mammalian elongation cycle by subunit rolling: a eukaryotic-specific ribosome rearrangement. Cell 158: 121–131). Image details show proteins, spacefilling representation, elongation factor TU—purple, 40S ribosomal protein S23—violet; RNA, ribbon representation, tRNA—brown, 18S rRNA-H5-H14—turquoise, 18S rRNA-H8—red, 18S rRNA-H44—purple, 28S rRNA-H89—green, 28S rRNA-H95—olive, mRNA—yellow. The image was generated with the Discovery Studio Visualizer. Cover image provided by the Jena Library of Biological Macromolecules—JenaLib (jenalib.fli-leibniz.de).