FIGURE 8.
(Top) The salient features of the rem1 gene elucidated in this study. (Bottom) Cotranscriptional models to account for the fates of mutant rem1 transcripts. The RNA processing events that unfold as RNA polymerase II (white on black stippling) traverses the wild-type rem1 gene in mid-meiotic cells (left, based on Fig. 1A, bottom, 5-h sample and Fig. 7A, 5-h meiotic control) or the mutant rem1 gene (black box = NCR substitution; x = 5′ splice site mutation) in proliferating cells (right, based on Fig. 5B, bottom, lane 6 and Fig. 7A, lane 6) are depicted. The size of each arrow indicates the relative yield of cryptically spliced and unspliced RNA.
