An energetically beneficial leader–linker interaction abolishes ligand-binding cooperativity in glycine riboswitches

(Downloading may take up to 30 seconds. If the slide opens in your browser, select File -> Save As to save it.)

Click on image to view larger version.

FIGURE 5.
FIGURE 5.

Representative semi-log plots of aptamers rescuing each other in trans in-line probing assays. (A) r7 of VCII133 rescued by 15 μM of aptamer I constructs. (B) r2 of VCI132LD and VCI132 rescued by 15 μM VCII133.

This Article

  1. RNA 18: 496-507