FIGURE 3.
Effect of RNAi repression of KREPB6, KREPB7, or KREPB8 on in vivo RNA editing. Real-time PCR analyses of mitochondrial RNAs from KREPB6 RNAi (A), KREPB7 RNAi (B), or KREPB8 RNAi (C) cell lines after 6 d of RNAi repression. Pre-edited (gray), edited (white), and control never edited ND4 (black) mRNA levels from the RNAi cells are shown relative to those of the same cell lines in which expression was not repressed by RNAi knockdown. The means and standard deviations from three independent experiments are shown. The thick black line at 1 indicates no relative change in mRNA level. β-Tubulin was used as the internal control.
