
Different possible scenarios for SNRNASM (single nucleotide resolution nucleic acid structure mapping) data. (A) RNA chemical probing data is collected, recorded in a laboratory notebook, and published in a manuscript as an elaborate, colorful figure. This allows the graduate student who collected the data to graduate. Unfortunately, the raw data, meticulously recorded in the laboratory notebook, becomes lost (Fogarty 2002). (B) Proposed alternative in which the data is stored in a computer, uploaded to a publicly available server (in the cloud), and made downloadable upon publication of the manuscript, allowing other investigators access for new analyses.










