Cover image

On the cover

Crystal structure of the Pyrococcus abyssi exosome RNase PH complexed with a single-stranded 10-merpoly(A) RNA (Protein Data Bank code: 2po1; Navarro MVAS, Oliveira CC, Zanchin NIT, Guimaraes BG. 2008. Insights into the mechanism of progressive RNA degradation by the archaeal exosome. J Biol Chem 283: 14120–14131.) Image details show RNA: surface representation, coloring according to the molecular electrostatic potential; proteins: cartoon representation, Rrp41 subunit—green, Rrp42 subunit—orange. The image was generated with the Accelrys Discovery Studio Visualizer. Cover image provided by the Jena Library of Biological Macromolecules—JenaLib (www.fli-leibniz.de/IMAGE.html).