Cover image

Cover Illustration: P-site and P/E-site tRNA structures used for comparison to a novel hybrid-site P-site tRNA in cryo-EM maps of a translation initiation complex (Protein Data Bank code: 1zo3; Allen, G.S., Zavialov, A., Gursky, R., Ehrenberg, M., and Frank, J. 2005. The Cryo-Em structure of a translation initiation complex from Escherichia coli. Cell 121: 703–712). Image details: RNA—ribbon, plates; ribbon—chain-specific coloring; A, red, U, magenta, C, purple, G, light green. The image was generated with the Accelrys Discovery Studio Visualizer and provided by the Jena Library of Biological Macromolecules (JenaLib; www.fli-leibniz.de/IMAGE.html).