The adenosine wedge: A new structural motif in ribosomal RNA
Abstract
Here, we present a new recurrent RNA arrangement, the so-called adenosine wedge (A-wedge), which is found in three places of the ribosomal RNA in both ribosomal subunits. The arrangement has a hierarchical structure, consisting of elements previously described as recurrent motifs, namely, the along-groove packing motif, the A-minor and the hook-turn. Within the A-wedge, these elements are involved in different types of cause–effect relationships, providing together for the particular tertiary structure of the motif.
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Footnotes
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Reprint requests to: Sergey V. Steinberg, Département de Biochimie, Université de Montréal, C.P. 6128, Succursale Centre-Ville, Montréal, Québec H3C 3J7, Canada; e-mail: serguei.chteinberg{at}umontreal.ca; fax: (514) 343-2210.
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Article published online ahead of print. Article and publication date are at http://www.rnajournal.org/cgi/doi/10.1261/rna.1550310.
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- Received January 8, 2009.
- Accepted November 5, 2009.
- Copyright © 2010 RNA Society
