Stereospecificity of short Rev-derived peptide interactions with RRE IIB RNA

TABLE 1.

Kd, nM, of RNA-peptide complexes at 20°C

Peptide D-RRE IIB L-RRE IIB M3 M4
LRevRh 14.4 ± 0.6 11 ± 3 59 ± 7 47 ± 6
LRev 31 ± 1 21.8 ± 0.6 179 ± 5 231 ± 4
DRev 14.6 ± 0.3 17.0 ± 0.4 29 ± 2 377 ± 23
LRevErse 42 ± 2 14.8 ± 0.1 38 ± 2 1160 ± 69
DRevErse 28 ± 1 22.6 ± 0.8 14.1 ± 0.4 121 ± 5
DrevMut1 1027 ± 52 — — —

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  1. RNA 9: 937-948

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