Characterization of the catalytic activity of U2 and U6 snRNAs

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FIGURE 6.
FIGURE 6.

Mutations in the AGC triad can block RNA X formation. (A) The effect of mutation of U6 G54 to A and U on RNA X formation. The position of RNA X and the U6 species used in each reaction is shown to the right. The concentration of Br in each lane is indicated above the panel. (B) Summary of the results of point mutations in the AGC triad. The U6 species used in each set of reactions is indicated below each series. The concentrations of Br tested in each series were 0.1, 1, 5, and 20 μM, and are graphed from left to right.

This Article

  1. RNA 9: 892-904