TABLE 1.
ADAR2 binding and editing of gus-PSTVd RNA constructs
| Binding to R/G stem–loop | Binding to segment 1a | Binding to backbone (not segment 1) | Editing specifically at R/G site | Number of nonselective editing sitesb | |
|---|---|---|---|---|---|
| aBinding to segment 1 is listed separately because this may be enhanced by the presence of the 5′ and 3′ ends of the molecule in this region. | |||||
| bFor determination of nonselective editing sites, 170 A residues in the backbone molecule were analyzed. | |||||
| (ND) Not determined. | |||||
| R/G wt | 94% | 4% | 2% | 86% | 15 |
| C42U46 | 83% | 12% | 5% | ND | ND |
| G56 | 67% | 22% | 11% | 35% | 17 |
