FIGURE 1.
The occurrence of in-frame (solid circles) nonsense codons in intron regions. The average for the two types of out-of-frame nonsense codons are included for comparison (open circles). The line represents the result expected by chance alone for an in-frame nonsense codon, using a Poisson distribution. (A) Pseudo exons; windows of 10 were grouped. (B) Flanks downstream from exons; windows of 5 were grouped; the starting point of each window is plotted. Lists of the sequences underlying this data can be found at www.columbia.edu/data/cu/biology/faculty/chasin/rnajournal.
