Structural organization of a viral IRES depends on the integrity of the GNRA motif

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FIGURE 6.
FIGURE 6.

Model of domain 3 structure in the FMDV IRES. (A) Results from partial T1, RNase A, and V1 digestion, together with DMS attack, have been assembled in a model of the secondary structure. Symbols and residues cited in the text are indicated. (B) Phylogenetic conservation of RNA structure in 26 different IRES sequences retrieved from databases.

This Article

  1. RNA 9: 1333-1344

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  1. August 2026, 32 (8)
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