
Structure of r-protein L4. (A) Sequence of the extended loop region of the E. coli r-protein L4 (201 amino acids total). The gray box indicates the region corresponding to the disordered structure in free L4 from T. maritima and extended loop in ribosome-bound L4 from Haloarcula marismortui. The extents of the deletions are shown. (▾) Amino acid which, when changed to glutamic acid, confers erythromycin resistance to E. coli. (B) Model of E. coli L4 drawn with RasMol (Bernstein 2000). The portions of the extended loop removed in the deletion mutants are indicated.










