Sex lethal and U2 small nuclear ribonucleoprotein auxiliary factor (U2AF65) recognize polypyrimidine tracts using multiple modes of binding

(Downloading may take up to 30 seconds. If the slide opens in your browser, select File -> Save As to save it.)

Click on image to view larger version.

FIGURE 4.
FIGURE 4.

RNA binding of SXL to wild type and various mutants of the tra NSS Py tract. Molar concentrations of recombinant GST–SXL are shown on the X-axis, and the fraction of RNA bound on the Y-axis. The sequences of various mutants are shown at the bottom, and the mutations are underlined. For simplicity, only the Py tracts are shown.

This Article

  1. RNA 9: 88-99

Current Issue

  1. July 2026, 32 (7)
  1. Current Issue
  1. Alert me to new issues of RNA