Characterization of human Smg5/7a: A protein with similarities to Caenorhabditis elegans SMG5 and SMG7 that functions in the dephosphorylation of Upf1

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FIGURE 1.FIGURE 1.
FIGURE 1.

hSmg5/7a amino acid and hSMG5/7a cDNA sequences. (A) The 1419-aa sequence of hSmg5/7a is numbered to the right. Underlined amino acids constitute regions of a putative PIN domain. Three predicted nuclear localization sequences are boxed. (B) The 5965-nt sequence of hSMG5/7a cDNA (KIAA0732) is numbered to the right. The ATG initiation codon, TGA termination codon, and AATAAA polyadenylation sequence are boxed; exon-exon junctions are labeled with bold vertical lines; and the 5′- and 3′-untranslated regions may be incomplete.

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  1. RNA 9: 77-87

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