Mechanism of molecular interactions for tRNA^Val recognition by valyl-tRNA synthetase

Interactions with the D- and T-loops of tRNA. (A) Interactions between the ValRS coiled-coil domain and tRNA^Val (stereoview). The trace of the phosphorus atoms of tRNA^Val is shown as a yellow tube. A20, U18•G55, and C19•G56 of tRNA^Val are shown as a ball-and-stick representation, where the carbon atoms are yellow. The ValRS coiled-coil domain is lime green. The ValRS amino acid residues that interact with the D- and T-loops of tRNA^Val are shown as a ball-and-stick representation, where the carbon atoms are green. (B) Interactions between the ArgRS N20-binding domain and tRNA^Arg (stereoview). The representation is the same as in Figure 6A, except that the ArgRS N20-binding domain is dark yellow.