Comprehensive mapping of the 5′ and 3′ untranslated regions of Aspergillus fumigatus reveals diverse mechanisms of mRNA processing including premature transcription termination

(Downloading may take up to 30 seconds. If the slide opens in your browser, select File -> Save As to save it.)

Click on image to view larger version.

FIGURE 6.
FIGURE 6.

Promoter proximal transcription termination occurs in A. fumigatus. Read alignment of (A) AFUB_004020 and (B) AFUB_039430, each encoding proteins of unknown function. The y-axis indicates total read counts for “-Seq” panels. Arrowheads indicate the positions of detected high-confidence 5′/3′ end sites. Read tracks were smoothened to improve viewability, and this infrequently masks some small introns. (C) Table depicting mean number of occurrences of the denoted Nrd1 and Nab3 binding sequences per designated sequence type (either ±100 or +500 nt as indicated). Sequences were taken from Webb et al. (2014).

This Article

  1. RNA 32: 250-266