Comprehensive mapping of the 5′ and 3′ untranslated regions of Aspergillus fumigatus reveals diverse mechanisms of mRNA processing including premature transcription termination

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FIGURE 4.
FIGURE 4.

Ssd1 and PUF binding sites are enriched in 5′ and 3′ UTRs, respectively. (A) Histogram showing the number of Ssd1 binding motifs in newly defined 5′ UTRs. Only genes with at least two motif occurrences were plotted. (B) GO-term analysis of the same genes as in A with a supplied background list of all genes with an identified 5′ UTR in our study. GO-term analysis was done using https://fungifun3.hki-jena.de/. (C) Percent of CNYTCNYT motif occurrence in different sequence types. For this graph, a single occurrence was also counted. (D) Potential PUF protein family binding motif occurrence in different sequence types. Indicated are the number of sequences with the respective motif and the percent of the total number of input sequences in brackets. Sequence motifs were taken from Hogan et al. (2015) and Wilinski et al. (2017).

This Article

  1. RNA 32: 250-266