Loop of fate: structural and mechanistic insights into hnRNPA1 binding to the hepatitis C virus RNA

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FIGURE 7.
FIGURE 7.

Model for 5BSL3.2Apical loop stem and UP1. The loop adenine residues are highlighted in purple, while the remaining loop residues are shown in red. The interactions of UP1 with the adenines of the loop region involve not only RRM1 and the linker region (cyan), but also suggest the proximity of RRM2 (blue), as indicated by 5BSL3.2 apical loop and RRM2 distance of ∼7 Å.

This Article

  1. Published in Advance November 24, 2025, doi: 10.1261/rna.080770.125 RNA 32: 215-236

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