Novel trinucleotide mRNA capping reagents: improved synthetic route and efficient cotranscriptional incorporation in mRNA

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FIGURE 7.
FIGURE 7.

Structure of “d(TTCT)” DNA template, T7 promoter, and alternative forms of mRNA that are being synthesized on this template with or without TCP (where xAm is either 6mAm or Am). Positions of transcription start site and DNAzyme cleavage site are shown with arrows and indicated for each product.

This Article

  1. Published in Advance November 19, 2025, doi: 10.1261/rna.080634.125 RNA 32: 195-214

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