PANTHER Score: Protein-Affinity for Nucleic Target-binding, Hybridization, and Energy Regression

TABLE 1.

Performance metrics of various machine learning models on the test set for PANTHER Score predictions

Model Test set
r MAE rs ρ-value
Random Forest Regression 0.80 1.79 0.77 0.04
GBoosting Regression 0.79 1.71 0.77 0.04
Neural Network 0.68 1.59 0.77 0.04
Stacked Ensemble 0.77 1.68 0.77 0.04
XGBoosting Regression 0.72 1.63 0.77 0.04
Linear Regression 0.69 1.62 0.52 0.22
  • Metrics include Pearson correlation coefficient (r), mean absolute error (MAE), Spearman's rank correlation coefficient (rs), and ρ-value.

This Article

  1. RNA 32: 131-149